Beta-carotene is converted in the body to vitamin A, which is necessary for good eye-sight and skin. Deficiency of vitamin A may cause night blindness . It also causes dry eyes[Xerosis],bitot spots, keratomalacia[softening of cornea], corneal opacities, eye infections, skin problems, and deficient growth. Some conditions may increase the need for beta-carotene or vitamin A. These include: Cystic fibrosis, diarrhoea, debilitating illness, injury, hepatic disease, malabsorption problems and pancreatic disease.

Prophylaxis for vitamin A difficiency: 3000-5000 IU/day. Treatment of established vitamin A deficiency: 50,000-100,000 IU/day I.M or oral for 1-3 days followed by intermittent supplement doses.

Contra Indications

It may be contraindicated in severe hepatic disease.

Precautions

Hypersensitivity reactions to the drug may occur. Precautions must be taken when taking the drug during pregnancy and breast-feeding. Excessive dosage leads to hypervitaminosis A.

Interactions

Regular use of liquid paraffin can result in vitamin A deficiency. Long term oral neomycin induces steatorrhea and interferes with vitamin A absorption.

Brand Names

Arovit drop[Roche]

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names

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