It is a snythetic PGE1 analogue. It is given orally and exerts a cytoprotective effect and also inhibits gastric acid secretion from the parietal cells. It exerts its effect on gastric secretion over a period of few hours.

Misoprostol is a drug that is used to prevent peptic ulcers and also recommended for prophylaxis of NSAID induced ulcers.

Routes of Administration and Dosage

Oral dose in Adults = 200 micrograms (mcg) four times a day or 400 mcg two times day

Contra Indications

It may be contraindicated in Epilepsy : Drugs like misoprostol have been shown to cause seizures. It is contraindicated in pregnancy.

Precautions

Precautions: During Lactation .Misoprostol is not recommended for use during breast-feeding because it may cause diarrhea in nursing babies. Allergies : may occur with the drug.

Interactions

It may rarely interact with other drugs.

Brand Names

Cytotec

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names

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