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Radiotherapy

  1. Isotopes: Elements with same Atomic number
  2. (Number of protons same, Number of Neutrons Vary)
  3. Most used materials for external irradiation- Cobalt 60 , Cesium 131 ( Gamma rays)
  4. Machine used for electron therapy- Betatron , Material used is Tungsten
  5. Substances used as permanent implant for radiation-
    • Gold Grains
    • Radon Seeds
  6. For permanent insertion into cavities
    • Colloidal Gold
    • Vitrium
    • Phosphorus 52
  7. Radio active phosphorus is useful in
Diagnosis of
  • Eye Cancers
  • Oesophageal Cancer
Treatment of –
  • Polycythemia Vera
  • Multiple Myeloma
  • Secondaries in Bone
  • Ca Prostate after priming with androgen.
  • Malignant ascites

Effect of Radiation on Tissues

Most Commonly affected Skin
Most Senstive Mucosa Intestinal Mucosa
Most Sensitive CNS part Mid Brain, Medulla, Spinal Cord
Most sensitive cell in CNS Neurone
Most Sensitive blood cells Lymphocytes
Most resistant Blood cells Platelets
Most sensitive organ in abdomen Kidney

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