Welcome, Guest    Sign in to Windows Live ID | Register  

  Industry Medical Portal |  Student Centre |  Sitemap |  Help 
FAQAbout Us |  Disclaimer & Legal |  Contact Us 

  Lisinopril

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names


Systems Cardiovascular System
Category Angiotensin Converting Enzyme Inhibitor


Pharmacokinetics

Lisinopril is slowly absorbed after oral administration. It has 1/2 life of 7 hrs. It is excreted via the urine.



Top

Indications

Losinopril inhibits Angiotensin Converting enzyme.It is used to treat hypertension. ACE inhibitors are also used to reduce proteinuria in diabetics. They are also used to treat congestive heart failure.



Top

Routes of Administration and Dosage

For oral dose (tablets): For congestive heart failure:Adults: 2.5 to 20 mg once a day.For Hypertension: Adults: 10 to 40 mg once a day.



Top

Contra Indications

Contraindicated in hypersensitivity, Pregnancy, aortic stenosis, renal impairment, corpulmonale, in children.



Top

Precautions

Allergies: Allergic reaction to Lisinopril may occur. Pregnancy: Studies in rats at doses many times the recommended human dose have shown that use of lisinopril causes a decrease in successful pregnancies, a decrease in the weight of infants, and an increase in infant deaths. It has also caused abnormal bone growth in rabbits.



Top

Interactions

Lithium and Indomethacin reduce hypotensive effect. Hydrochlorthiazide potentiates its effect. Co-administration of cyclo-oxygenase causes reduction in renal function.



Top

Brand Names

Acebitor (Croydon), Acetitor (Croydon), Acinopril (Boehringer Mannheim), Biopril(Biochem), Cipril (Cipla), Hipral( Micro Labs), Ilis (Recon), Inras (Merind), Linvas(Cadila Pharma), Lipril (Lupin), Lisace (Anglo French), Lisicard (Gufic), Lisinace (Alkem), Lisir 5/10 (Kramer), Lislo (SPPL), Lisoril (IPCA), Listril (Torrent), LPL (Concept), Nivant (German Remedies), Odace (Alidac), Prevace (Sertec), Sinopril (Themis Pharma).



Top

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names

|

 

Advertisement
Tell us what you think about Web Health Centre - Send us your feedback
Copyright © 2012 WebHealthCentre. All rights reserved. Brought to you by